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何玉龙
5.4我来评喜爱度
所在大学:南京大学
所在院系:生命科学学院
所在地区:江苏
所在城市:南京
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何玉龙老师介绍
何玉龙 PhD
遗传学,教授,博士生导师
电话
办公室:58641512
实验室:58641522
电子邮件 :
yhe20005@yahoo.com
yulong.he@nicemice.cn
研究兴趣:
血管新生 (angiogenesis) 与淋巴管新生 (lymphangiogenesis) 的分子调控,以及肿瘤转移的分子机制。
代表论文:
Holopainen T#, Huang H#, Chen C# (co-first author), Kim KE, Zhang L, Zhou F, Han W, Li C, Yu J, Wu J, Koh GY, Alitalo K, He Y. Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and establishment. Cancer Res 69:4656-64 (2009). IF: 8.649
Tammela T, He Y(co-first author), Lyytikk? J, Jeltsch M, Markkanen J, Pajusola K, Yl?-Herttuala S, Alitalo K. Distinct Architecture of Lymphatic Vessels Induced by Chimeric Vascular Endothelial Growth Factor-C/Vascular Endothelial Growth Factor Heparin-Binding Domain Fusion Proteins. Circ Res 100:1468-75 (2007). IF: 9.408
He Y, Rajantie I, Pajusola K, Jeltsch M, Holopainen T, Yla-Herttuala S, Harding T, Jooss K, Takahashi T, Alitalo K. VEGFR-3 mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res 65:4739-46(2005). IF: 8.649
He Y, Rajantie I, Ilmonen M, Makinen T, Karkkainen MJ, Haiko P, Salven P, Alitalo K. Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis . Cancer Res 64:3737-40 (2004). IF: 8.649
He Y, Karpanen T and Alitalo K. Role of lymphangiogenic factors in lymphatic tumor metastasis. Biochim Biophys Acta 1654:3-12 (2004). IF: 8.395
He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst 94:785-7 (2002). IF: 13.844
He Y, Smith SK, Day KA, Clark D, Licence DR, Charnock-Jones DS. Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocrinol 13:537-545 (1999). IF: 5.708
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