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杨雪松老师介绍
杨雪松，男，医学博士，教授。哈尔滨医科大学医疗系本科，哈尔滨医科大学生理学硕士，日本东京医科齿科大学医学部生理学博士，英国Manchester大学博士后，而后在英国Dundee大学始建发育生物学课题组，利用长期科研工作中积累的microscopy结合组织学、细胞和分子生物学技术开始鸡胚胎原肠胚形成期三胚层细胞迁移模式和FGF、PDGF和VEGF信号调节细胞迁移过程的研究，部分研究成果已经发表在高影响因子的国际学术期刊上（Developmental Cell、Current Biology、PNAS、Development、Developmental Biology、JBC、JP等）。回国在暨南大学继续从事“早期胚胎发育三胚层形成过程中细胞迁移的基因调控”这个发育生物学主课题的同时，利用这个成熟试验模式进行血管发生过程中的基因调控、癌细胞的周边组织侵蚀和癌细胞转移、胚胎干细胞利用、发育过程中细胞迁移的生物数学模型等。
各阶段发表的代表性论文：
1. Xuesong Yang, Holly Chrisman and Cornelis J. Weijer: PDGF signaling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development 2008 Oct 135 (21): 3521-3530 (暨南大学)
2 Qiaoyun Yue, Laura Wagstaff, Xuesong Yang, Cornelis Weijer and Andrea Munsterberg: Wnt3a- mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development 2008 Mar 135 (6): 1029-1037 (暨南大学)
3 Tadahiro Iimura, Xuesong Yang, Cornelis J. Weijer, Olivier Pourquie: Dual mode of paraxial mesoderm formation during chick gastrulation. PNAS 2007 Feb 20; 104(8): 2744-2749
4 Nick R. Leslie*, Xuesong Yang* (*共同第一作者), C.Peter Downes and Cornelis J. Weijer: PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration. Current Biology 2007 Jan 23; 17(2): 115-25
5 Manli Chuai, Wei Zeng, Xuesong Yang, Veronika Boychenko, James Glazier, Cornelis J Weijer: Cell Movement during Chick Primitive Streak Formation. Developmental Biology 2006 Aug 1; 296(1): 137-49
6 Nick R. Leslie, Xuesong Yang, C. Peter Downes, Cornelis J. Weijer: The regulation of cell migration by PTEN. Biochemical Society Transanctions 2005; 33: 1507-1508
7 Cheng Cui, Xuesong Yang, Manli Chuai, James A. Glazier and Cornelis J. Weijer: Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Developmental Biology 2005 Aug 1; 284(1): 37-47
8 Xuesong Yang, Dirk Dormann, Andrea E. Munsterberg, Cornelis J. Weijer: Cell Movement Patterns during Gastrulation in the Chick Are Controlled by Positive and Negative Chemotaxis Mediated by FGF4 and FGF8. Developmental Cell 2002; 3(3): 425-37
9 G. Szalmay, G. Varga, F. Kajiyama. XS Yang, T. Lang, R.M. Maynard, M.C. Steward: Bicarbonate and fluid secretion evoked by cholecystokinin, bombesin and acetylcholine in isolated guinea-pig pancreatic ducts. Journal of Physiology 2001; 535(3): 795-807
10 J. Bruce, XS Yang, C. Ferguson, A.C. Elliott, M.C. Steward, R.M. Case, D. Riccardi: Molecular and functional evidence of a Ca+2 (polyvalent cation)-sensing receptor in rat pancreas. The Journal of Biological Chemistry. 1999; 274(29): 20561-20568
11 Xuesong Yang, Kohtaro Kamino: Photometric assessment of volume changes coupled with membrane potential in valinomycin-incorporated red blood cell. The Japanese Journal of Physiology. 1997; 47(2): 217-230
12 Yoko Momose-Sato, Katsushige Sato, Akihiko Hirota, Tetsuro Sakai, Xuesong Yang, Kohtaro Kamino: Optical Characterization of a novel GABA response in early embryonic chick brainstem. Neuroscience. 1997; 80(1): 203-219
13 Xuesong Yang, Kohtaro Kamino: Photometric determination of phenomenological correlation between osmotic behavior and haemolysis of red blood cells. The Japanese Journal of Physiology. 1995; 45(5): 723-741
各阶段发表的代表性论文：
1. Xuesong Yang, Holly Chrisman and Cornelis J. Weijer: PDGF signaling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development 2008 Oct 135 (21): 3521-3530 (暨南大学)
2 Qiaoyun Yue, Laura Wagstaff, Xuesong Yang, Cornelis Weijer and Andrea Munsterberg: Wnt3a- mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development 2008 Mar 135 (6): 1029-1037 (暨南大学)
3 Tadahiro Iimura, Xuesong Yang, Cornelis J. Weijer, Olivier Pourquie: Dual mode of paraxial mesoderm formation during chick gastrulation. PNAS 2007 Feb 20; 104(8): 2744-2749
4 Nick R. Leslie*, Xuesong Yang* (*共同第一作者), C.Peter Downes and Cornelis J. Weijer: PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration. Current Biology 2007 Jan 23; 17(2): 115-25
5 Manli Chuai, Wei Zeng, Xuesong Yang, Veronika Boychenko, James Glazier, Cornelis J Weijer: Cell Movement during Chick Primitive Streak Formation. Developmental Biology 2006 Aug 1; 296(1): 137-49
6 Nick R. Leslie, Xuesong Yang, C. Peter Downes, Cornelis J. Weijer: The regulation of cell migration by PTEN. Biochemical Society Transanctions 2005; 33: 1507-1508
7 Cheng Cui, Xuesong Yang, Manli Chuai, James A. Glazier and Cornelis J. Weijer: Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Developmental Biology 2005 Aug 1; 284(1): 37-47
8 Xuesong Yang, Dirk Dormann, Andrea E. Munsterberg, Cornelis J. Weijer: Cell Movement Patterns during Gastrulation in the Chick Are Controlled by Positive and Negative Chemotaxis Mediated by FGF4 and FGF8. Developmental Cell 2002; 3(3): 425-37
9 G. Szalmay, G. Varga, F. Kajiyama. XS Yang, T. Lang, R.M. Maynard, M.C. Steward: Bicarbonate and fluid secretion evoked by cholecystokinin, bombesin and acetylcholine in isolated guinea-pig pancreatic ducts. Journal of Physiology 2001; 535(3): 795-807
10 J. Bruce, XS Yang, C. Ferguson, A.C. Elliott, M.C. Steward, R.M. Case, D. Riccardi: Molecular and functional evidence of a Ca+2 (polyvalent cation)-sensing receptor in rat pancreas. The Journal of Biological Chemistry. 1999; 274(29): 20561-20568
11 Xuesong Yang, Kohtaro Kamino: Photometric assessment of volume changes coupled with membrane potential in valinomycin-incorporated red blood cell. The Japanese Journal of Physiology. 1997; 47(2): 217-230
12 Yoko Momose-Sato, Katsushige Sato, Akihiko Hirota, Tetsuro Sakai, Xuesong Yang, Kohtaro Kamino: Optical Characterization of a novel GABA response in early embryonic chick brainstem. Neuroscience. 1997; 80(1): 203-219
13 Xuesong Yang, Kohtaro Kamino: Photometric determination of phenomenological correlation between osmotic behavior and haemolysis of red blood cells. The Japanese Journal of Physiology. 1995; 45(5): 723-741
杨雪松老师相关教学资源
- 暨南大学教学资源
- 杨雪松老师课程教学资源
