从1,500,000教师库中查找（输入学校名称或教师姓名）
李俊发老师介绍
姓名：李俊发 性别：男 职称：教授
职务：神经生物学系副主任；分子生物学实验测试室主任
招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕)
招生专业：疼痛医学(博) 疼痛医学(硕)
研究方向名称：分子神经生物学
电子信箱：junfali@ccmu.edu.cn
社会任职
1. 中国生理学会理事
2. 北京生理科学会秘书长
3. 美国生物化学和分子生物学会(ASBMB)、中国生物化学和分子生物学会、中国生理学会、北京生理科学会、北京神经科学会等学术团体会员。
4. 《生理通讯》主编
5. 《基础医学与临床》常务编委
6. 《中华眼底病杂志》编委
7. 《生理学报》、《生理科学进展》、《中华医学杂志》、《中国科技论文在线》、《自然科学进展》和《International Journal of Biological Sciences》等杂志审稿专家。
8. 《Journal of Neuroscience Methods》和《Cellular and Molecular Biology Letters》等SCI杂志审稿专家
个人简历
1. 198109-198608:首都医科大学 医学学士
2. 198608-198908:北京医学高等专科学校(现首都医科大学燕京医学院) 助教，兼校团委书记
3. 198908-199206:中国协和医科大学 医学硕士
4. 199206-199602:北京医学高等专科学校(现首都医科大学燕京医学院) 讲师，兼教务处副处长
5. 199602-200102:美国国立卫生研究院(NIH) 访问学者
6. 200102-200612:首都医科大学神经生物学系 副研究员/副教授、副主任
7. 200308-200607:首都医科大学 神经生物学博士
8. 200501- :首都医科大学分子生物学实验测试室 主任
9. 200505-200508:美国德州大学医学部(UTMB) 访问研究员
10. 200701- :首都医科大学神经生物学系 教授、副主任
重要学术论文
1. Liu Y, Li J(李俊发)*, Yang J, Ji F, Bu X, Zhang N, Zhang B.Inhibition of PKCgamma membrane translocation mediated morphine preconditioning-induced neuroprotection against oxygen-glucose deprivationin the hippocampus slices of mice. Neuroscience Letters. 2008,Accepted:已接收.SCI
2. Qi X, Lin W, Li J(李俊发), Li H, Wang W, Wang D, Sun M.Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiology of Disease. 2008,31(2):278-285.SCI
3. Wei Y, Wang N, Lu Q, Zhang N, Zheng D, Li J(李俊发)*.Enhanced protein expressions of sortilin and p75NTR in retina of rat following. Neuroscience Letters. 2007,429(2-3):169-174.SCI
4. Zhang N, Gao G, Bu X, Han X, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice. Neuroscience Letters. Neuroscience Letters. 2007,423(3):219-224.SCI
5. Huang P, Qi Z, Bu X, Zhang N, Han S, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of mitogen- and stress-activated protein kinase-1 involved in cerebral hypoxic preconditioning of mice. Journal of Neuroscience Research. 2007,85(6):1279-1287.SCI
6. Wu J, Su G, Ma L, Zhang X, Lei Y, Lin Q, Nauta HJ, Li J(李俊发)*, Fang L.The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain. Neurochemistry International. 2007,50(5):710–718.SCI
7. Jia J, Wang X, Li H, Han S, Zu P, Li J(李俊发)*.Activations of nPKCe and ERK1/2 were involved in oxygen-glucose deprivation induced neuroprotection via NMDA receptors in hippocampal slices of mice. Journal of Neurosurgical Anesthesiology. 2007,19(1):18-24.SCI
8. Kadekaro M, Su G, Chu R, Lei Y, Li J(李俊发)*, Fang L.Effects of nitric oxide on expressions of nitrosocysteine and calcium-activated potassium channels in the supraoptic nuclei and neural lobe of dehydrated rats. Neuroscience Letters. 2007,411(2):117-122.SCI
9. Qi Z, Bu X, Huang P, Zhang N, Han S, Fang L, Li J(李俊发)*.Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice. Neurochemical Research. 2007,32(9):1450-1459.SCI
10. Bu X, Huang P, Qi Z, Zhang N, Han S, Fang L, Li J(李俊发)*.Cell type-specific activation of p38 mitogen-activated protein kinases in the brain regions of hypoxic preconditioned mice. Neurochemistry International. 2007,51(8):459-466.SCI
11. Wu J, Li J(李俊发), Lin Q, Fang L.Signal transduction in chronic pain. International Anesthesiology Clinics. 2007,45(2):73-81.
12. Li J(李俊发)*, Yang C, Han S, Zu P, Wu J, Xu Q, Fang L.Increased phosphorylation of neurogranin in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,391(3):150-153.SCI
13. Qi X, Lin W, Li J(李俊发), Pan Y, Wang W.The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behavioural Brain Research. 2006,175(2):233-240.SCI
14. Li J(李俊发)*, Qu Y, Zu P, Han S, Gao G, Xu Q, Fang L.Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia. Brain Research. 2006,1093(1):25-32.SCI
15. Long C, Gao Y, Gao G, Han S, Zu P, Fang L, Li J(李俊发)*.Decreased phosphorylation and protein expression of ERK1/2 in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,397(3):307-312.SCI
16. Gao Y, Gao G, Long C, Han S, Zu P, Fang L, Li J(李俊发)*.Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure. Biochemical and Biophysical Research Communications. 2006,340(2):661-667.SCI
17. Zhao L, Wang N, Jiang L, Long C, Li J(李俊发)*.Unilateral optic nerve transection up-regulate Hsp70 protein expression in lateral geniculate nucleus of rats. Neuroscience Letters. 2006,404(1-2):44-49.SCI
18. Kadekaro-M，Su G，Chu R，Lei Y，Li J(李俊发)*，Fang L.Nitirc oxide up-regulates the expression of calcium-dependent potassium channels in thesuproptic nuclei and neueal lobe of rats following dehdration. Neuroscience Letters. 2006,404(1-2):50-55.SCI
19. Meng F, Li J(李俊发), Zhang B, Ji F.nPKCe and NMDA receptors participate in neuroprotection induced by morphine pretreatment. Journal of Neurosurgical Anesthesiology. 2006,18(2):119-124.SCI
20. Wu J, Su G, Ma L, Zhang X, Lei Y, Li J(李俊发), Lin Q, Fang L.Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection. Molecular Pain. 2005,1:26-34.
21. Niu C, Li J(李俊发)*, Cui X, Han S, Zu P, Li H, Xu Q.Changes in cPKC isoform-specific membrane translocation and protein expression in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2005,384(1-2):1-6.SCI
22. Cai CM, Sun BC, Liu XY, Wang JJ, Li J(李俊发), Han S, Wang NL, Lu QJ.RNA interference inhibits expression of vascular endothelial growth factor (VEGF) in human retinal pigment epithelial cells. CHINESE MED J-PEKING (Engl). 2005,118:1907-1911.SCI
23. Li J(李俊发)*, Niu C, Han S, Zu P, Li H, Xu Q, Fang L.Identification of protein kinase C isoforms involved in cerebral hypoxic preconditioning of mice. Brain Research. 2005,1060(1-2):62-72.SCI
24. Huang KP, Huang FL, Jager T, Li J(李俊发), Reymann KG, Balschun D.Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling. Journal of Neuroscience. 2004,24(47):10660-10669.SCI
25. Wu J, Li J(李俊发), Huang KP, Huang FL.Attenuation of protein kinase C and camp-dependent protein kinase signal transduction in the neurogranin knockout mouse. Journal of Biological Chemistry (JBC). 2002,277(22):19498-19505.SCI
26. Li J(李俊发), Huang FL and Huang KP.Glutathiolation of proteins by glutathione disulfide S-oxide derived from S-nitrosoglutathione. Modifications of rat brain neurogranin/RC3 and neuromodulin/GAP-43. Journal of Biological Chemistry (JBC). 2001,276(5):3098-3150.SCI
27. Liu J, He L, Collins I, Ge H, Libutti D, Li J(李俊发), Egly J, and Levens D.The FBP interacting repressor targets TFIIH to inhibit activated transcription. Molecular Cell. 2000,5:331-341.SCI
28. Huang KP, Huang FL, Li J(李俊发), Schuck P, McPhie P.Calcium-sensitive interaction between calmodulin and modified forms of rat brain neurogranin/RC3. Biochemistry. 2000,39(24):7291-7299.SCI
29. Pak JH, Huang FL, Li J(李俊发), Balschun D, Reymann KG, Chiang C, Westphal H, and Huang KP.Involvement of neurogranin in the modulation of calcium/calmodulin- dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice. Proc Natl Acad Sci U S A (PNAS). 2000,97(21):11232-11237.SCI
30. Li J(李俊发), Pak JH, Huang FL and Huang KP.N-methyl-D-aspartate induces neurogranin/RC3 oxidation in rat brain slices. Journal of Biological Chemistry (JBC). 1999,274(3):1294-1300.SCI
主编或副主编的著作/译著
1. 《细胞信号转导研究技术》,主编,中国协和医科大学出版社,200808
重要奖项
1. 中青年骨干教师培养计划 北京市教委 200506
2. 优秀青年教师资助计划 国家教育部 200208
3. 张锡钧基金会全国青年优秀生理学学术论文奖 三 199307
4. 北京市高等学校优秀青年骨干教师 北京市教委 199208
Copyright ? 1999-2006 BY GS CPUMS All Rights Reserved.
主办/版权：首都医科大学研究生院 访问量：12397484
管理员：李学谨 Email：lixuejin@ccmu.edu.cn
职务：神经生物学系副主任；分子生物学实验测试室主任
招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕)
招生专业：疼痛医学(博) 疼痛医学(硕)
研究方向名称：分子神经生物学
电子信箱：junfali@ccmu.edu.cn
社会任职
1. 中国生理学会理事
2. 北京生理科学会秘书长
3. 美国生物化学和分子生物学会(ASBMB)、中国生物化学和分子生物学会、中国生理学会、北京生理科学会、北京神经科学会等学术团体会员。
4. 《生理通讯》主编
5. 《基础医学与临床》常务编委
6. 《中华眼底病杂志》编委
7. 《生理学报》、《生理科学进展》、《中华医学杂志》、《中国科技论文在线》、《自然科学进展》和《International Journal of Biological Sciences》等杂志审稿专家。
8. 《Journal of Neuroscience Methods》和《Cellular and Molecular Biology Letters》等SCI杂志审稿专家
个人简历
1. 198109-198608:首都医科大学 医学学士
2. 198608-198908:北京医学高等专科学校(现首都医科大学燕京医学院) 助教，兼校团委书记
3. 198908-199206:中国协和医科大学 医学硕士
4. 199206-199602:北京医学高等专科学校(现首都医科大学燕京医学院) 讲师，兼教务处副处长
5. 199602-200102:美国国立卫生研究院(NIH) 访问学者
6. 200102-200612:首都医科大学神经生物学系 副研究员/副教授、副主任
7. 200308-200607:首都医科大学 神经生物学博士
8. 200501- :首都医科大学分子生物学实验测试室 主任
9. 200505-200508:美国德州大学医学部(UTMB) 访问研究员
10. 200701- :首都医科大学神经生物学系 教授、副主任
重要学术论文
1. Liu Y, Li J(李俊发)*, Yang J, Ji F, Bu X, Zhang N, Zhang B.Inhibition of PKCgamma membrane translocation mediated morphine preconditioning-induced neuroprotection against oxygen-glucose deprivationin the hippocampus slices of mice. Neuroscience Letters. 2008,Accepted:已接收.SCI
2. Qi X, Lin W, Li J(李俊发), Li H, Wang W, Wang D, Sun M.Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiology of Disease. 2008,31(2):278-285.SCI
3. Wei Y, Wang N, Lu Q, Zhang N, Zheng D, Li J(李俊发)*.Enhanced protein expressions of sortilin and p75NTR in retina of rat following. Neuroscience Letters. 2007,429(2-3):169-174.SCI
4. Zhang N, Gao G, Bu X, Han X, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice. Neuroscience Letters. Neuroscience Letters. 2007,423(3):219-224.SCI
5. Huang P, Qi Z, Bu X, Zhang N, Han S, Fang L, Li J(李俊发)*.Neuron-specific phosphorylation of mitogen- and stress-activated protein kinase-1 involved in cerebral hypoxic preconditioning of mice. Journal of Neuroscience Research. 2007,85(6):1279-1287.SCI
6. Wu J, Su G, Ma L, Zhang X, Lei Y, Lin Q, Nauta HJ, Li J(李俊发)*, Fang L.The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain. Neurochemistry International. 2007,50(5):710–718.SCI
7. Jia J, Wang X, Li H, Han S, Zu P, Li J(李俊发)*.Activations of nPKCe and ERK1/2 were involved in oxygen-glucose deprivation induced neuroprotection via NMDA receptors in hippocampal slices of mice. Journal of Neurosurgical Anesthesiology. 2007,19(1):18-24.SCI
8. Kadekaro M, Su G, Chu R, Lei Y, Li J(李俊发)*, Fang L.Effects of nitric oxide on expressions of nitrosocysteine and calcium-activated potassium channels in the supraoptic nuclei and neural lobe of dehydrated rats. Neuroscience Letters. 2007,411(2):117-122.SCI
9. Qi Z, Bu X, Huang P, Zhang N, Han S, Fang L, Li J(李俊发)*.Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice. Neurochemical Research. 2007,32(9):1450-1459.SCI
10. Bu X, Huang P, Qi Z, Zhang N, Han S, Fang L, Li J(李俊发)*.Cell type-specific activation of p38 mitogen-activated protein kinases in the brain regions of hypoxic preconditioned mice. Neurochemistry International. 2007,51(8):459-466.SCI
11. Wu J, Li J(李俊发), Lin Q, Fang L.Signal transduction in chronic pain. International Anesthesiology Clinics. 2007,45(2):73-81.
12. Li J(李俊发)*, Yang C, Han S, Zu P, Wu J, Xu Q, Fang L.Increased phosphorylation of neurogranin in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,391(3):150-153.SCI
13. Qi X, Lin W, Li J(李俊发), Pan Y, Wang W.The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behavioural Brain Research. 2006,175(2):233-240.SCI
14. Li J(李俊发)*, Qu Y, Zu P, Han S, Gao G, Xu Q, Fang L.Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia. Brain Research. 2006,1093(1):25-32.SCI
15. Long C, Gao Y, Gao G, Han S, Zu P, Fang L, Li J(李俊发)*.Decreased phosphorylation and protein expression of ERK1/2 in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2006,397(3):307-312.SCI
16. Gao Y, Gao G, Long C, Han S, Zu P, Fang L, Li J(李俊发)*.Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure. Biochemical and Biophysical Research Communications. 2006,340(2):661-667.SCI
17. Zhao L, Wang N, Jiang L, Long C, Li J(李俊发)*.Unilateral optic nerve transection up-regulate Hsp70 protein expression in lateral geniculate nucleus of rats. Neuroscience Letters. 2006,404(1-2):44-49.SCI
18. Kadekaro-M，Su G，Chu R，Lei Y，Li J(李俊发)*，Fang L.Nitirc oxide up-regulates the expression of calcium-dependent potassium channels in thesuproptic nuclei and neueal lobe of rats following dehdration. Neuroscience Letters. 2006,404(1-2):50-55.SCI
19. Meng F, Li J(李俊发), Zhang B, Ji F.nPKCe and NMDA receptors participate in neuroprotection induced by morphine pretreatment. Journal of Neurosurgical Anesthesiology. 2006,18(2):119-124.SCI
20. Wu J, Su G, Ma L, Zhang X, Lei Y, Li J(李俊发), Lin Q, Fang L.Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection. Molecular Pain. 2005,1:26-34.
21. Niu C, Li J(李俊发)*, Cui X, Han S, Zu P, Li H, Xu Q.Changes in cPKC isoform-specific membrane translocation and protein expression in the brain of hypoxic preconditioned mice. Neuroscience Letters. 2005,384(1-2):1-6.SCI
22. Cai CM, Sun BC, Liu XY, Wang JJ, Li J(李俊发), Han S, Wang NL, Lu QJ.RNA interference inhibits expression of vascular endothelial growth factor (VEGF) in human retinal pigment epithelial cells. CHINESE MED J-PEKING (Engl). 2005,118:1907-1911.SCI
23. Li J(李俊发)*, Niu C, Han S, Zu P, Li H, Xu Q, Fang L.Identification of protein kinase C isoforms involved in cerebral hypoxic preconditioning of mice. Brain Research. 2005,1060(1-2):62-72.SCI
24. Huang KP, Huang FL, Jager T, Li J(李俊发), Reymann KG, Balschun D.Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling. Journal of Neuroscience. 2004,24(47):10660-10669.SCI
25. Wu J, Li J(李俊发), Huang KP, Huang FL.Attenuation of protein kinase C and camp-dependent protein kinase signal transduction in the neurogranin knockout mouse. Journal of Biological Chemistry (JBC). 2002,277(22):19498-19505.SCI
26. Li J(李俊发), Huang FL and Huang KP.Glutathiolation of proteins by glutathione disulfide S-oxide derived from S-nitrosoglutathione. Modifications of rat brain neurogranin/RC3 and neuromodulin/GAP-43. Journal of Biological Chemistry (JBC). 2001,276(5):3098-3150.SCI
27. Liu J, He L, Collins I, Ge H, Libutti D, Li J(李俊发), Egly J, and Levens D.The FBP interacting repressor targets TFIIH to inhibit activated transcription. Molecular Cell. 2000,5:331-341.SCI
28. Huang KP, Huang FL, Li J(李俊发), Schuck P, McPhie P.Calcium-sensitive interaction between calmodulin and modified forms of rat brain neurogranin/RC3. Biochemistry. 2000,39(24):7291-7299.SCI
29. Pak JH, Huang FL, Li J(李俊发), Balschun D, Reymann KG, Chiang C, Westphal H, and Huang KP.Involvement of neurogranin in the modulation of calcium/calmodulin- dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice. Proc Natl Acad Sci U S A (PNAS). 2000,97(21):11232-11237.SCI
30. Li J(李俊发), Pak JH, Huang FL and Huang KP.N-methyl-D-aspartate induces neurogranin/RC3 oxidation in rat brain slices. Journal of Biological Chemistry (JBC). 1999,274(3):1294-1300.SCI
主编或副主编的著作/译著
1. 《细胞信号转导研究技术》,主编,中国协和医科大学出版社,200808
重要奖项
1. 中青年骨干教师培养计划 北京市教委 200506
2. 优秀青年教师资助计划 国家教育部 200208
3. 张锡钧基金会全国青年优秀生理学学术论文奖 三 199307
4. 北京市高等学校优秀青年骨干教师 北京市教委 199208
Copyright ? 1999-2006 BY GS CPUMS All Rights Reserved.
主办/版权：首都医科大学研究生院 访问量：12397484
管理员：李学谨 Email：lixuejin@ccmu.edu.cn
