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王学敏老师介绍
王学敏，长江学者讲座教授
学 历
1982年，华中农业大学农学学士
1984年，俄亥俄州立大学遗传学硕士
1987年，肯塔基大学植物生理生化学博士
职 历
2007-至今, 华中农业大学生命科学技术学院长江学者讲座教授
2004-至今，特聘教授，密苏里大学（圣.路易斯）
2004-至今，研究员，Danforth 植物科学研究中心，圣.路易斯
2000-2004，教授，生物化学，堪萨斯州立大学
2000-2004，兼职教授，生物学，堪萨斯州立大学
1997-2000，副教授，生物化学，堪萨斯州立大学
1991-1997，助理教授，生物学，堪萨斯州立大学
1988-1991，路易斯安那州立大学博士后
研究方向
植物脂质代谢，信号转导
主要兼职
国际期刊Plant Signaling and Behavior 和J. Biol. Chem.编委; 美国国家基金评审专家; 堪萨斯州立大学生物化学兼职教授;
电 话
027-87281131(O)
电子邮件
wangxue@umsl.edu.cn
工作单位
华中农业大学生命科学院，作物遗传改良国家重点实验室
研究成果
发表SCI文章近100篇，近期代表作如下
1. Wang X, Zhang W, Li W, Mishra G. 2007. Phospholipid signaling in plant response to drought and salt stress. In Advances in Molecular Breeding towards Salinity. Eds, M Jenks, P Hasegawa, Springer pp. 183-192.IF：
2. Welti R, Isaac G, Tamura P, Esch SW, Sparks A, Jeannotte R, Roth M, Maatta S, Williams TD, Shah J, Wang X. 2007. Lipid profiling: Analysis of gene function and physiological responses in Arabidopsis. In Current Advances in the Biochemistry and Cell Biology of Plant Lipids. Eds, C. Benning, J. Ohlrogge pp. 287-291
3. Welti R, Shah J, Li W, Li M, Chen J, Burke JJ, Fauconnier ML, Chapman K, Chye ML, Wang X. 2007. Plant lipidomics: discerning biological function by profiling plant complex lipids using mass spectrometry. Front. Biosci. 12:2494-2506.
4. Esch SW, Tamura P, Sparks AA, Roth MR, Devaiah SP, Heinz E, Wang X, Williams TD, Welti R. 2007. Rapid characterization of fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry. J Lipid Res. 48:235-241
5. Welti R, Roth M, Deng Y, Shah J, Wang X. 2007. Lipidomics: ESI-MS MS-based profiling to determine the function of genes involved in metabolism of complex lipids. In Concepts in Plant Metabolomics, Springer, Dordrecht, The Netherlands. Eds, N. Basil and E.S. Wurtele. pp 87-92.
6. Mishra, G, Zhang W, Deng F, Zhao J, Wang X. 2006. A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis. Science 312: 264-266.
7. Li M, Qin C, Welti R, Wang X. 2006. Double knockouts of phospholipase Dζ1 and ζ2 in Arabidopsis affect root elongation during phosphate-limited growth, but do not affect root hair patterning. Plant Physiol. 140: 761-770
8. Li M, Welti R, Wang X. 2006. Quantitative profiling of Arabidopsis polar glycerolipids in response to phosphorus starvation. Roles of phospholipases D zeta1 and D zeta2 in phosphatidylcholine hydrolysis and digalactosyldiacylglycerol accumulation in phosphorus-starved plants. Plant Physiol. 142:750-761.
9. Wang X, Devaiah SD, Zhang W, Welti R. 2006. Signaling functions of phosphatidic acid. Prog. Lipid Research 45: 250-278.
10. Qin C, Li M, Qin W, Bahn SC, Wang C, Wang X. 2006. Expression and characterization of Arabidopsis phospholipase Dgamma2. Biochim. Biophys. Acta. 1761: 1450-1458
11. Devaiah SP, Roth MR, Baughman E, Li M, Welti R, Wang X. 2006. Lipid Profiling to quantitatively display polar glycerolipid species and the role of phospholipase Dα1 in the species in Arabidopsis tissues. Phytochemistry 67: 1907-1924.
12. Rajashekar CB, Zhou HE, Zhang Y, Li W, Wang X. 2006. Suppression of phospholipase Dalpha1 induces freezing tolerance in Arabidopsis: response of cold-responsive genes and osmolyte accumulation. J. Plant Physiol. 163:916-926.
13. Zhang Y, Li SZ, Li J, Pan X, Cahoon RE, Jaworski JG, Wang X, Jez JM, Chen F, Yu O. 2006. Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and Mammalian cells. J. Am. Chem Soc. 128:13030-13030.
14. Wang X, Li W, Li M, Welti R. 2006. Profiling lipid changes in plant response to low temperatures. Physiol. Plant. 126:90-96
15. Wang X. 2006. Phospholipid-derived signaling in plant response to temperature and water stresses. Genetic Engineering, 27: 57-66.
16. Zhang W, Yu L, Zhang Y, Wang X. 2005. Phospholipase D in the signaling network of plant responses to abscisic acid and reactive oxygen species Biochim. Biophys. Acta 1736:1-9.
17. Wang X. 2005. Regulatory functions of phospholipase D and phosphatidic acid in plant growth development, and stress responses. Plant Physiol. 139:566-573
18. Welt, R, Shah J, LeVine S, Esch W, Williams T, Wang X. 2005. High throughput lipid profiling to identify and characterize genes involved in lipid metabolism, signaling, and stress response. In Functional Lipidomics. Edited by L. Feng and G. Prestwich, CRC Press , Boca Raton, FL. pp. 308-320.
19. Zhang W, Qin C, Zhao J, Wang X. 2004. Phospholipase Da1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling. Proc. Natl. Acad. Sci. USA 101: 9508-9513.
20. Li W, Li M, Zhang W, Welti R, Wang X. 2004. The plasma membrane-bound phospholipase Dd enhances freezing tolerance in Arabidopsis. Nature Biotech. 22: 427-433.
21. Zhao J, Wang X. 2004. Arabidopsis phospholipase Dα1 interacts with the heterotrimeric G-protein α-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors. J. Biol. Chem. 279:1794-1800.
22. Pappan K, Zheng L, Krishnamoorthi R, Wang X. 2004. Evidence for and characterization of Ca2+ binding to the catalytic region of Arabidopsis thaliana phospholipase DβJ. Biol. Chem. 279: 47833-47839.
23. Wang X. 2004. Lipid signaling. Curr. Opin. Plant Biol. 7: 329-336
24. Welti R, Wang X. 2004. Lipid species profiling: A high throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling. Curr. Opin. Plant Biol. 7: 337-344
学 历
1982年，华中农业大学农学学士
1984年，俄亥俄州立大学遗传学硕士
1987年，肯塔基大学植物生理生化学博士
职 历
2007-至今, 华中农业大学生命科学技术学院长江学者讲座教授
2004-至今，特聘教授，密苏里大学（圣.路易斯）
2004-至今，研究员，Danforth 植物科学研究中心，圣.路易斯
2000-2004，教授，生物化学，堪萨斯州立大学
2000-2004，兼职教授，生物学，堪萨斯州立大学
1997-2000，副教授，生物化学，堪萨斯州立大学
1991-1997，助理教授，生物学，堪萨斯州立大学
1988-1991，路易斯安那州立大学博士后
研究方向
植物脂质代谢，信号转导
主要兼职
国际期刊Plant Signaling and Behavior 和J. Biol. Chem.编委; 美国国家基金评审专家; 堪萨斯州立大学生物化学兼职教授;
电 话
027-87281131(O)
电子邮件
wangxue@umsl.edu.cn
工作单位
华中农业大学生命科学院，作物遗传改良国家重点实验室
研究成果
发表SCI文章近100篇，近期代表作如下
1. Wang X, Zhang W, Li W, Mishra G. 2007. Phospholipid signaling in plant response to drought and salt stress. In Advances in Molecular Breeding towards Salinity. Eds, M Jenks, P Hasegawa, Springer pp. 183-192.IF：
2. Welti R, Isaac G, Tamura P, Esch SW, Sparks A, Jeannotte R, Roth M, Maatta S, Williams TD, Shah J, Wang X. 2007. Lipid profiling: Analysis of gene function and physiological responses in Arabidopsis. In Current Advances in the Biochemistry and Cell Biology of Plant Lipids. Eds, C. Benning, J. Ohlrogge pp. 287-291
3. Welti R, Shah J, Li W, Li M, Chen J, Burke JJ, Fauconnier ML, Chapman K, Chye ML, Wang X. 2007. Plant lipidomics: discerning biological function by profiling plant complex lipids using mass spectrometry. Front. Biosci. 12:2494-2506.
4. Esch SW, Tamura P, Sparks AA, Roth MR, Devaiah SP, Heinz E, Wang X, Williams TD, Welti R. 2007. Rapid characterization of fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry. J Lipid Res. 48:235-241
5. Welti R, Roth M, Deng Y, Shah J, Wang X. 2007. Lipidomics: ESI-MS MS-based profiling to determine the function of genes involved in metabolism of complex lipids. In Concepts in Plant Metabolomics, Springer, Dordrecht, The Netherlands. Eds, N. Basil and E.S. Wurtele. pp 87-92.
6. Mishra, G, Zhang W, Deng F, Zhao J, Wang X. 2006. A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis. Science 312: 264-266.
7. Li M, Qin C, Welti R, Wang X. 2006. Double knockouts of phospholipase Dζ1 and ζ2 in Arabidopsis affect root elongation during phosphate-limited growth, but do not affect root hair patterning. Plant Physiol. 140: 761-770
8. Li M, Welti R, Wang X. 2006. Quantitative profiling of Arabidopsis polar glycerolipids in response to phosphorus starvation. Roles of phospholipases D zeta1 and D zeta2 in phosphatidylcholine hydrolysis and digalactosyldiacylglycerol accumulation in phosphorus-starved plants. Plant Physiol. 142:750-761.
9. Wang X, Devaiah SD, Zhang W, Welti R. 2006. Signaling functions of phosphatidic acid. Prog. Lipid Research 45: 250-278.
10. Qin C, Li M, Qin W, Bahn SC, Wang C, Wang X. 2006. Expression and characterization of Arabidopsis phospholipase Dgamma2. Biochim. Biophys. Acta. 1761: 1450-1458
11. Devaiah SP, Roth MR, Baughman E, Li M, Welti R, Wang X. 2006. Lipid Profiling to quantitatively display polar glycerolipid species and the role of phospholipase Dα1 in the species in Arabidopsis tissues. Phytochemistry 67: 1907-1924.
12. Rajashekar CB, Zhou HE, Zhang Y, Li W, Wang X. 2006. Suppression of phospholipase Dalpha1 induces freezing tolerance in Arabidopsis: response of cold-responsive genes and osmolyte accumulation. J. Plant Physiol. 163:916-926.
13. Zhang Y, Li SZ, Li J, Pan X, Cahoon RE, Jaworski JG, Wang X, Jez JM, Chen F, Yu O. 2006. Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and Mammalian cells. J. Am. Chem Soc. 128:13030-13030.
14. Wang X, Li W, Li M, Welti R. 2006. Profiling lipid changes in plant response to low temperatures. Physiol. Plant. 126:90-96
15. Wang X. 2006. Phospholipid-derived signaling in plant response to temperature and water stresses. Genetic Engineering, 27: 57-66.
16. Zhang W, Yu L, Zhang Y, Wang X. 2005. Phospholipase D in the signaling network of plant responses to abscisic acid and reactive oxygen species Biochim. Biophys. Acta 1736:1-9.
17. Wang X. 2005. Regulatory functions of phospholipase D and phosphatidic acid in plant growth development, and stress responses. Plant Physiol. 139:566-573
18. Welt, R, Shah J, LeVine S, Esch W, Williams T, Wang X. 2005. High throughput lipid profiling to identify and characterize genes involved in lipid metabolism, signaling, and stress response. In Functional Lipidomics. Edited by L. Feng and G. Prestwich, CRC Press , Boca Raton, FL. pp. 308-320.
19. Zhang W, Qin C, Zhao J, Wang X. 2004. Phospholipase Da1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling. Proc. Natl. Acad. Sci. USA 101: 9508-9513.
20. Li W, Li M, Zhang W, Welti R, Wang X. 2004. The plasma membrane-bound phospholipase Dd enhances freezing tolerance in Arabidopsis. Nature Biotech. 22: 427-433.
21. Zhao J, Wang X. 2004. Arabidopsis phospholipase Dα1 interacts with the heterotrimeric G-protein α-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors. J. Biol. Chem. 279:1794-1800.
22. Pappan K, Zheng L, Krishnamoorthi R, Wang X. 2004. Evidence for and characterization of Ca2+ binding to the catalytic region of Arabidopsis thaliana phospholipase DβJ. Biol. Chem. 279: 47833-47839.
23. Wang X. 2004. Lipid signaling. Curr. Opin. Plant Biol. 7: 329-336
24. Welti R, Wang X. 2004. Lipid species profiling: A high throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling. Curr. Opin. Plant Biol. 7: 337-344
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