梁好均 理学博士
中国科学技术大学 高分子科学与工程系
教授 博士生导师
Tel: 0551-3607824 (Office)
0551-3600240 (Lab)
E-mail: hjliang@ustc.edu.cn
个人简介
梁好均，教授，1963年5月生于吉林。1984年7月毕业于东北师范大学物理系；1990年12月于长春应用化学研究所获博士学位。2002年中国科学技术大学教授。1999. 12 – 2000. 8月香港中文大学化学系访问学者；2000. 12 – 2001. 9英国Loughborough 大学材料系访问学者；2003. 9 - 11美国SUNY Buffalo大学生物物理系访问学者。研究集中在高分子材料设计、制备、高分子凝聚态物理和生物物理中的理论与计算等方面。内容包括蛋白质与蛋白质、DNA、合成大分子及有机分子间相互作用；多肽、合成大分子及有机小分子药物设计；杂链大分子及蛋白质单链折叠和设计；大分子粗粒化模型建立及多尺度模拟；杂链大分子及蛋白质在熔体、溶液状态下组装及聚集；聚合物材料表面改性。先后承担国家自然科学基金、国家973计划等研究课题。在Macromolecules, J. Chem. Phys., J. Phys. Chem. B, Phys. Rev. E 等期刊杂志上发表SCI文章60余篇。2005年国家杰出青年基金获得者。The Open Chemical Physics Journal, International Journal of Polymer Science和《高分子学报》杂志编委。
研究方向
1. 高分子凝聚态物理理论计算与模拟
2. 生物物理实验
研究兴趣:采用理论计算和模拟方法研究如下问题
1. 蛋白质与蛋白质、DNA、合成大分子及有机分子间相互作用
2. 多肽、合成大分子及有机小分子药物设计
3. 杂链大分子及蛋白质单链折叠和设计
4. 大分子粗粒化模型建立及多尺度模拟
5. 杂链大分子及蛋白质在熔体、溶液状态下组装及聚集
采用的研究手段包括：理论计算MC, MD, DPD, SCFT, DDFT等；实验DPI, NMR, Raman等。
欢迎对软物质科学理论计算、模拟和实验有兴趣的同学报考本实验室研究生，并招收具有上述背景的博士后研究人员。
承担项目
1． 杂链大分子折叠、设计和自组装机理的研究: 国家杰出青年基金
2． 微囊藻毒素吸附树脂设计与制备：国家自然科学基金面上项目
3． 两亲性嵌段聚合物在水溶液中自组装的计算与模拟：国家自然科学基金面上项目
4． 聚烯烃的多重结构及其高性能化的基础研究：973国家重点基础研究发展计划
近期代表性论文
1. Li XJ, Guo JY, Liu Y & Liang HJ Microphase separation of diblock copolymer poly(styrene-b-isoprene): A dissipative particle dynamics simulation study. J. Chem. Phys. 2009, 130, 074908
2. Li SB, Chen P, Wang XH, Zhang LX & Liang HJ Surface-induced morphologies of lamella-forming diblock copolymers confined in nanorod arrays. J. Chem. Phys. 2009, 130, 014902
3. Xu BS, Yang YD, Liang HJ & Yaoqi Zhou An all-atom knowledge-based energy function for protein-DNA threading, docking decoy discrimination, and prediction of transcription-factor binding profiles Proteins: Structure, Function and Bioinformatics 2009, On line (DOI: 10.1002/prot.22384)
4. Li XJ, Liu Y, Wang L, Deng MG & Liang HJ Fusion and fission pathways of vesicles from amphiphilic triblock copolymers: A dissipative particle dynamics simulation study. Phys. Chem. Chem. Phys.2009 Accepted (DOI: 10.1039/B817773B)
5. He LL, Zhang LX & Liang HJ Microdomain Morphology of Lamella-Forming Diblock Copolymer Confined in a Thin Film. J. Polym. Sci. B. 2009, 40, 1
6. He LL, Zhang LX & Liang HJ Cooperative surface-induced self-assembly of symmetric diblock copolymers confined films with embedded nanorods Polymer 2009, 50, 721
7. Chen P, Liang HJ & Shi AC Microstructures of a Cylinder-Forming Diblock Copolymer under Spherical Confinement. Macromolecules 2008, 41, 8938
8. Li XJ, Deng MG, Liu Y & Liang HJ Dissipative Particle Dynamics Simulations of Toroidal Structure Formations of Amphiphilic Triblock Copolymers. J. Phys. Chem. B 2008, 47, 14762
9. Chen P & Liang HJ Cylinder-forming triblock terpolymer in nanopores: A Monte Carlo simulation study. J. Phys. Chem. B 2008, 112, 1918
10. Chen T, Lin XS, Liu Y, Lu T & Liang HJ Microcanonical analyses of homopolymer aggregation processes. Phys. Rev. E 2008, 78, 056101
11. Su JY, Zhang LX & Liang HJ The phase behavior of polyethylene ring chains. J. Chem. Phys. 2008, 129, 044905
12. He LL, Zhang LX & Liang HJ Effects of nanoparticles on the lamellar phase separation of diblock copolymers.J. Phys. Chem. B 2008, 112, 4194
13. Chen P, Liang HJ & Shi AC Origin of microstructures from confined asymmetric diblock copolymers. Macromolecules 2007, 40, 7329
14. Chen T, Lin X, Liu Y & Liang HJ Microcanonical analysis of association of hydrophobic segments in a heteropolymer Phys. Rev. E 2007, 76, 046110
15. Li XJ, Kou DZ, Rao SL & Liang HJ Developing a coarse-grained force field for the diblock copolymer poly(styrene-b-butadiene) from atomistic simulation. J. Chem. Phys. 2006, 124, 204909
16. Chen P, He XH & Liang HJ Effect of surface field on the morphology of a symmetric diblock copolymer under cylindrical confinement. J. Chem. Phys. 2006, 124, 104906.
17. Chen P & Liang HJ Monte Carlo simulations of cylinder-forming ABC triblock terpolymer thin films. J. Phys. Chem. B 2006, 110, 18212.
18. Kou DZ & Liang HJ Microstructures from a Mixture of ABC 3-Miktoarm Star Terpolymers and Homopolymers. J. Phys. Chem. B 2006, 110, 23557.
19. Huang R, Jiang Y & Liang HJ Effect of architecture on the tensile properties of triblock copolymers in a lamellar phase. ChemPhysChem 2006, 7, 1950.
20. Li X, Jiang Y, Li YC & Liang HJ Influence of electric field on the phase transitions of the hexagonal cylinder phase of diblock copolymers. ChemPhysChem 2006, 7, 1693
21. Huang L, Ma XJ & Liang HJ What is the origin of those common structures of protein-model chains? Polymer 2006, 47, 1755
22. Jiang Y, Huang R & Liang HJ Effect of polydispersity on the tensile modulus of diblock copolymers in a lamellar phase J. Chem. Phys. 2005, 123, 124906
23. Jiang Y, Zhu JT, Jiang W & Liang HJ Cornucopian cylindrical aggregate morphologies from self-assembly of amphiphilic triblock copolymer in selective media J. Phys. Chem. B 2005, 109, 21549
24. Zhu JT, Jiang Y, Liang HJ & Jiang W Self-assembly of ABA amphiphilic triblock copolymers into vesicles in dilute solution J. Phys. Chem. B. 2005, 109, 8619
25. Jiang Y, Yan XY, Liang HJ & Shi AC Effect of polydispersity on the phase diagrams of linear ABC triblock copolymers in two dimensions J. Phys. Chem. B 2005, 109, 21047
26. Jiang Y, Liang HJ & Shi AC Effect of polydispersity on the formation of vesicles from amphiphilic diblock copolymers Macromolecules 2005, 38, 6710
27. Li XJ, Huang L & Liang HJ Developing coarse-grained force fields for cis-poly(1,4-butadiene) from the atomistic simulation Polymer 2005, 46, 6507
28. Sun DC, Huang L & Liang HJ Unstable inverted phases of di- and tri-block copolymers on solution-casting films Macromolecules Research 2005, 13, 152
29. Lu T, He XH & Liang HJ Ordered Microstructures by assembly of ABC 3-miktoarm star terpolymers and linear hompolymers J. Chem. Phys. 2004, 121, 9702
30. Xu BS, Huang L & Liang HJ Thermodynamic behaviors of polyampholytes at low temperatures J. Chem. Phys. 2004, 121, 7494
31. He XH, Liang HJ, Huang L & Pan CY Complex microstructures of amiphiphilic diblock copolymer in dilute solution J. Phys. Chem. B 2004, 108, 1731
32. Dai B, Song M, Hourston DJ, He XH, Liang HJ & Pan CY Influence of block lengths and symmetries of block copolymers on phase behavior of polymer A/polymer B/block copolymer ternary blends Polymer, 2004, 45 1019
33. Huang L, He XH, He TB & Liang HJ A cunning strategy in design of polymeric nanomaterials with novel microstructures J. Chem. Phys. 2003, 119, 12479
34. Huang L, Xe XH, Wang YY, Chen HN & Liang HJ Phase transition of short chains at ultra low temperature J. Chem. Phys. 2003, 119, 2432
35. He XH, Huang L, Liang HJ & Pan CY Localizations of junction points of ABC 3-miktoarm star terpolymers J. Chem. Phys. 2003, 118, 9861
36. He XH, Liang HJ & Pan CY Self-condensing vinyl polymerization in the presence of multifunctional initiator with unequal rate constants: Monte Carlo simulation Polymer 2003, 44, 6697
37. Huang L, He XH, Huang LS & Liang HJ Computer simulationon the self-assembly of associating polymers Polymer 2003, 44, 1967
38. He XH, Huang L, Liang HJ & Pan CY Self-assebly of star block copolymers by dynamic density functional theory J. Chem. Phys. 2002, 116, 10508
39. Liang HJ & Wang YY Influence of monomer types on the designability of a protein-model chain Chin. Phys. Lett. 2002, 19, 1382
40. He XH, Liang HJ, Song M & Pan CY Possibility of design of nanodevices by confined macromolecular self-assembly Macromol. Theor Simul. 2002, 11, 379
41. Wang YU, Chen HN, Liang HJ Monte Carlo simulation on the thermodynamic properties of a heteropolymer chain J. Chem. Phys. 2001, 115, 3951
42. He XH, Song M, Liang HJ & Pan CY Self-assembly of the symmetric diblock copolymer in a confined state: Monte Carlo simulation. J. Chem. Phys. 2001,114, 10510
43. He XH, Liang HJ & Pan CY Monte Carlo simulation of morphologies of self-assembled amphiphilic diblock copolymer in solution. Phys. Rev. E 2001, 63, 031804
44. He XH, Liang HJ & Pan CY Monte Carlo simulation of hyperbranched copolymerizations in the presence of a multifunctional initiator Macromol. Theor Simul. 2001, 10, 196
45. Liang HJ, Jiang W & He XH Monte Carlo simulation of pulsed-laser polymerization in emulsion Eur. Polym. J. 2000, 6, 2527
46. Liang HJ & Chen HN First-order transition of a homopolymer chain with Lennard-Jones potential J. Chem. Phys. 2000, 113, 4469
47. Liang HJ Designability of a protein chain in an off-lattice heteropolymer model J. Chem. Phys. 2000, 113, 4827
48. Liang HJ, Li FH & He XH Monte Carlo simulation for the modification of polymer via grafting Eur. Polym. J. 2000, 36, 1613
49. Liang HJ Observation of the molten globule state in a Monte Carlo simulation of the coil-to-globule transition of a homopolymer chain. J. Chem. Phys. 1999, 110, 10212
50. Liang HJ Compatibility of triblock copolymers in an A/B/copolymer ternary mixture Macromolecules 1999, 32, 8204
51. Liang HJ, He, XH, Jiang W & Jiang B. Monte Carlo simulation of phase separation of the A/B/A-B ternary mixture Macromol. Theory Simul. 1999, 8, 173
Last updated on Mar. 8 2009